Premature graying of hair, or canities, can significantly impact individuals’ self-esteem as it is often associated with old age. Hair pigmentation is due to melanin produced by melanocytes, with genes and signaling pathways influencing hair color. Graying of hair is linked to oxidative stress, autoimmune diseases, and genetic factors. Factors such as UV radiation, emotional stress, and nutritional deficiencies can also contribute to premature graying. Treatment options include plucking gray hair, addressing nutritional deficiencies, and using hair dyes made from natural or synthetic products. Further research is needed to explore the associations between premature graying and various health conditions.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6290285/