Scientists have long debated how the brain clears molecular waste, potentially explaining why sleep is refreshing. No one knows the purpose of cerebrospinal fluid circulating in the brain, with some proposing it as a brain highway. Recent research at the University of Rochester suggests that the brain’s blood vessels may push cerebrospinal fluid around, potentially draining waste. The glymphatic system hypothesis, suggesting that cerebrospinal fluid moves waste during sleep, is controversial. Some researchers question the accuracy of the theory, but it remains popular for filling gaps in brain understanding. The brain’s waste-clearance system continues to puzzle scientists, emphasizing the need for further research and discussion.
https://www.quantamagazine.org/the-mysterious-flow-of-fluid-in-the-brain-20250326/