Researchers have used the protein-structure-prediction tool AlphaFold to identify hundreds of thousands of potential psychedelic molecules that could be used in the development of new antidepressants. AlphaFold’s predictions, which are easily accessible, have been shown to be just as useful as experimentally derived protein structures for drug discovery. Some scientists have expressed skepticism about the accuracy of AlphaFold’s predictions, but recent research has demonstrated that the tool can be successful in identifying promising drug candidates. The ability to predict protein structures using AlphaFold could revolutionize drug discovery by providing researchers with a quick and convenient way to identify potential medicines.
https://www.nature.com/articles/d41586-024-00130-8