A groundbreaking new treatment called Trikafta has revolutionized the lives of patients with cystic fibrosis, a disease that once guaranteed an early death. Trikafta thins mucus in the lungs and has allowed patients to live longer than ever before. Patients experience a dramatic improvement in lung function, coughing up years of accumulated mucus in a process they call the Purge. Trikafta is not a cure, but it has changed the prognosis for those with cystic fibrosis. Many patients who take it can now expect to live a normal lifespan. The drug is a prime example of the success of personalized medicine, targeting the specific genetic mutation that causes the disease.
https://www.theatlantic.com/magazine/archive/2024/04/cystic-fibrosis-trikafta-breakthrough-treatment/677471/