Researchers at the University of Bonn have developed an aptamer cream to combat allergic contact dermatitis in mice. The aptamer binds to immune system messenger substances, inhibiting their function, resulting in decreased allergic reactions. Surprisingly, this method was effective even when the cream was applied topically. Aptamers are single-stranded DNA molecules that can bind to specific molecules depending on their sequence, making them a promising avenue for active ingredient research. The researchers are hopeful that this aptamer cream could be used to treat other skin conditions such as atopic dermatitis and melanoma. However, further studies are needed to determine its effectiveness in humans.
https://medicalxpress.com/news/2024-07-ointment-dna-molecules-combat-allergic.html