A groundbreaking study led by the Singh Lab at McMaster University has discovered a new pathway that cancer cells use to infiltrate the brain, specifically in glioblastoma, the most aggressive form of brain cancer. This research offers hope for new treatments, including a therapy that can block and kill these tumors. The study, published in Nature Medicine on Aug. 2, 2024, shows a promising new treatment that destroys returning cancer cells in preclinical animal models. By targeting a protein called Roundabout Guidance Receptor 1 (ROBO1) with CAR T cells, researchers have seen significant results in multiple brain cancer models.
https://medicalxpress.com/news/2024-08-therapy-treatment-glioblastoma-cells-newly.html