Histotripsy, a technique that uses sound waves to break down tumors, has been approved by the U.S. Food and Drug Administration (FDA) for liver treatment. Developed at the University of Michigan, histotripsy provides a noninvasive alternative to traditional cancer treatments like surgery, chemotherapy, and radiation, which often have significant side effects. HistoSonics, a company co-founded by U-M engineers and doctors, has received clearance from the FDA to use histotripsy to destroy targeted liver tissue. The technique works by using ultrasound waves to form microbubbles within the tumor, causing it to break apart and be cleared by the immune system. Histotripsy also has potential benefits beyond tumor destruction, as it can stimulate the immune system to fight cancer cells. The next step is to combine histotripsy with immunotherapy or drug delivery to treat tumors throughout the body.
https://news.umich.edu/tumor-destroying-sound-waves-receive-fda-approval-for-liver-treatment-in-humans/