Cell therapy repairs cornea damage with patient’s stem cells gives trial results

Massachusetts Eye and Ear, in collaboration with other institutions, has conducted a phase I trial of a stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC) for patients with severe chemical burns in one eye. The treatment involves taking stem cells from the patient’s healthy eye, growing them on a graft, and then transplanting them back into the damaged eye. Early results from the trial show promising outcomes, with restored cornea surfaces and improvements in vision for the patients. The researchers aim to fill a critical treatment gap for patients with untreatable vision loss and pain due to cornea injuries.


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